Multiple sclerosis: Novel immunotherapy reverses paralysis in mice - Medical News Today

In multiple sclerosis (MS), the immune system mistakingly attacks myelin - the protective coating of nerve fibers - in the central nervous system .

When myelin or the underlying nerve fibers are damaged, communication between the brain and spinal cord is disrupted. This triggers an array of symptoms, including walking difficulties, numbness or tingling in the face, body, or extremities, and muscle weakness.

In the new study , lead investigator Christopher Jewell, Ph.D., of the University of Maryland, and colleagues found a way to reprogram immune cells to stop attacking myelin in mouse models of MS, which restored the rodents' ability to walk.

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